Inflammation and sleep disorders

Inflammation independently of its origin including chronic autoimmune arthritis, irritable bowel syndrome, etc. destroys body biological clock functioning and leads to sleep and shiftwork-type disorders.

How the body clock controls inflammation
The cause is that in inflammatory diseases, a genetic factor NF-kappa beta (NFKB) catalysts the tissues destruction and at the same time violates the body’s biological clock. This interaction between the inflammation and body biological clocks is not only relevant to understanding how inflammation affects the brain and sleep-wake cycle but also how immune cells work.

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